Notify feminine sufferers of reproductive prospective that utilization of OXYCONTIN for an prolonged time frame in the course of pregnancy can result in neonatal opioid withdrawal syndrome, which can be life-threatening Otherwise recognized and dealt with [see WARNINGS AND PRECAUTIONS and Use In Distinct Populations].
Avoid taking in grapefruit or drinking grapefruit juice while using this medication Except if your medical doctor or pharmacist states you could do so properly. Grapefruit can improve the chance of Unwanted effects with this medicine. Talk to your medical professional or pharmacist for more facts.
Oxycodone could greatly enhance the neuromuscular blocking motion of skeletal muscle mass relaxants and produce a heightened degree of respiratory despair.
Don't use the prolonged-launch form of oxycodone To ease ache that is certainly mild or that may disappear in a few days. This medication is just not for occasional ("as desired") use.
Oxycodone hydrochloride tablets need to be applied with Intense caution in sufferers with significant Long-term obstructive pulmonary disease or cor pulmonale, and in clients getting significantly diminished respiratory reserve, hypoxia, hypercapnia, or pre-current respiratory melancholy.
Oxycodone causes a reduction in motility involved with an increase in clean muscle mass tone during the antrum of your tummy and duodenum. Digestion of meals from the small intestine is delayed and propulsive contractions are lowered.
Extensive-expression scientific studies haven't been done in animals to evaluate the carcinogenic opportunity of oxycodone hydrochloride tablets or oxycodone. The probable effects on male or female fertility have not been researched in animals.
Whilst serious, everyday living-threatening, or fatal respiratory depression can happen at any time in the course of the use of OXYCONTIN, the risk is biggest in the initiation of therapy or following a dosage increase.
The respiratory depressant outcomes of narcotics as well as their capacity to elevate cerebrospinal fluid force could be markedly exaggerated in the presence of head harm, other intracranial lesions or even a pre-present increase in intracranial stress.
Ladies of childbearing possible who get more info become, or are planning to become, Expecting really should be recommended to refer to their medical professional concerning the results of analgesics together with other drug use in the course of pregnancy on on their own as well as their unborn boy or girl.
To minimize the chance of choking or click here obtaining issues swallowing the tablet, choose just one a tablet at any given time Should your dose is for more than one tablet. Never pre-soak, lick, or wet the tablet just before placing it as part of your mouth. Be sure to drink plenty of h2o with Each and every tablet to swallow it fully.
Separately titrate OXYCONTIN to a dosage that provides adequate get more info analgesia and minimizes adverse reactions. Constantly reevaluate clients getting OXYCONTIN to assess the maintenance of agony Handle, signals and indications of opioid withdrawal, together with other adverse reactions, in addition to to reassess for the development of habit, abuse and misuse [see WARNINGS AND Safety measures].
This drug passes into breast milk and could possibly have unwanted outcomes over a nursing infant. read more Notify the health practitioner at once if your infant develops uncommon sleepiness, problems feeding, or issues respiratory. Talk to your medical professional in advance of breastfeeding.
Storage Store at space temperature from gentle and dampness. Never store in the bathroom. Preserve all drugs faraway from small children and Animals. See also Warning more info part.